New insights into cortisol levels in PTSD

New insights into cortisol levels in PTSD.

The article ‘‘Relationship of cortisol, norepinephrine, and epinephrine levels with war-induced posttraumatic stress disorder in fathers and their offspring’’ by Yahyavi et al. provided interesting data on the neuroendocrinology of post-traumatic stress disorder (PTSD). The mechanisms that underlie the associations of cortisol levels with traumatic exposures and PTSD are still not well understo...

Increased hair cortisol levels in PTSD

New Insights into the Effect of Diabetes and Obesity in Alzheimer’s Disease

Abstract Alzheimer’s disease (AD) is the most common cause of dementia in elderly people. The prevalence of Alzheimer diseases is increasing in the world due to population aging. Metabolic disease such as diabetes and obesity play important role in Alzheimer disease. Hyperglycemia can play important role in brain damage. It causes cognitive impairments, functional and structural alterations in...

Induction of secondary axis in hydra revisited: New insights into pattern formation

In 1909, several years before the famous `Organizer’ experiments of Spemann and Mangold, Ethel Browne demonstrated induction of a secondary axis in hydra by grafting a hypostome. Based on this and subsequent work, in the late sixties, Lewis Wolpert proposed the theory of morphogen gradients and positional information. We have studied secondary axis induction by hypostome and foot tissue using t...

New insights into the role of cortisol and the glucocorticoid receptor in severe depression.

Belanoff et al (2002) reported in this issue of Biological Psychiatry that the antiglucocorticoid mifepristone is effective in treating psychotic depression. If replicated in a placebo-controlled study, this finding will have important implications for the treatment of mood disorders for several reasons. It provides a possible new treatment for psychotic depression, the most difficult of the de...